當(dāng)細(xì)胞失去控制時，癌癥就會出現(xiàn)。解讀癌細(xì)胞的“藍(lán)圖” - 概述癌細(xì)胞如何劫持特定途徑以實現(xiàn)不受控制的擴(kuò)散 - 將導(dǎo)致更有效的方法來對抗它。來自魏茨曼科學(xué)研究所的科學(xué)家和來

While the amount of small non-coding RNA sequencing data is continuously increasing, it is still unclear to which extent small RNAs are represented in the human genome. Saarland University researchers have analyzed 303 billion sequencing rea

雖然小的非編碼RNA測序數(shù)據(jù)的數(shù)量不斷增加，但仍然不清楚小RNA在人類基因組中的代表程度。薩爾大學(xué)的研究人員已經(jīng)分析了來自近25,000個數(shù)據(jù)集的3030億個測序讀數(shù)來回答這個問題。

While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a p

　雖然我們體內(nèi)的許多細(xì)胞可以積累致癌突變，但這些事件中的大多數(shù)不會導(dǎo)致腫瘤形成，因為這些異常細(xì)胞被防御機制消除。相反，當(dāng)突變發(fā)生在對其特異性敏感的特定細(xì)胞類型中時

單細(xì)胞mRNA測序(scRNA-seq)允許分析異質(zhì)細(xì)胞群，提供解決各種生物和醫(yī)學(xué)問題的令人興奮的可能性。最近開發(fā)了一系列方法，因此有必要系統(tǒng)地比較它們的靈敏度，準(zhǔn)確度，精度和成本效

Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has been recently developed, making it nece

To treat and prevent pregnancy-related disorders, researchers must understand not only what can go wrong, but when. Complications, such as preeclampsia and pre-term birth, often occur in the second or third trimester, and most research to da